ventolin^3 wrote:
Deanouk wrote:The general public show little symptoms of toxoplasmosis because they aren't training twice a day and putting their body through unnatural stress levels that elite sportsmen do
no
you seem to have no clue about medicine
the general public show little symptoms because they have trivial exposure
for coe to have been ill to skip '83wc indicates massive exposure which is not inconsistent with parentral contraction of protozoa
No, missing the 83 Worlds is not indicative of 'massive exposure' at all. He was feeling crap, yet still able to run 1:43 & 3:34 times. He was in pain, hadn't been able to train properly for months and was advised to pull out and rest.
Elite athletes often present with persisting fatigue and recurrent infections. Training loads and excessive competition may contribute to these symptoms, but, if they do not resolve with adequate rest, clinical investigation is warranted. It may be difficult to differentiate between “healthy” tiredness related to training at an elite level and fatigue of a pathological nature. Fatigue in an athlete may be considered pathological if it is not reversed by a period of rest or decreased training and is accompanied by a decrease in performance. Elite athletes with recurrent infections may also present with associated fatigue, or the fatigue may depend on other factors.
A recent study (2003) at the Australian Institute of Sport retrospectively assessed the incidence of upper respiratory tract infections (URTI) in elite swimmers; the conclusion was that the incidence was no higher than in the general Australian population. However, four or more episodes of URTI a year are generally considered a higher incidence than normal for the Australian population and worthy of clinical assessment. This is especially important in athletes when these infections cause disruption to training and this leads to suboptimal performance or an inability to compete.
In this study, 41 competitive athletes complaining of persistent fatigue and/or recurrent infections had a thorough medical examination and a series of clinical investigations to exclude the possibility of underlying sinister pathology and to identify causes for their fatigue and susceptibility to infection. An emphasis was placed on causes of URTI, as these are the major cause of infections in elite athletes.
The 41 subjects (22 male, 19 female) were recruited from competitive athletes who presented to the Clinic complaining of fatigue and/or recurrent infections.
Subjects provided an extensive medical history and had a thorough medical examination to establish if there were any underlying medical conditions. Saliva and blood samples were referred to the Pathology Service. Reference ranges appropriate for elite athletes were used to assess pathology test results. Pathology investigations included a full blood count, erythrocyte sedimentation rate, iron studies (including total iron, total iron binding capacity, ferritin), and vitamin B12 and folate measurements. A full biochemical profile included glucose concentration, creatine kinase activity, and renal, liver and thyroid function tests. A screen of infectious disease included serology for hepatitis A, B, and C, toxoplasmosis, cytomegalovirus, EBV, and Ross River virus.
The most common condition identified in this group was partial humoral immune deficiency (11/40, 28%). Most of these athletes (10/11) had an IgG3 subclass deficiency. One athlete had a partial serum IgA deficiency. Another commonly identified organic condition was recent or unresolved viral infection (11/41, 27%). Evidence of IgM seropositivity was found for cytomegalovirus (five cases), EBV (three cases), Ross River virus (one case), toxoplasmosis (one case), and mycoplasma (one case).
Although people can be infected through contact with cat feces, the far more common way for someone to have contact with the parasite that causes toxoplasmosis is through unhygienic handling of raw or undercooked meat, drinking contaminated water and exposure to garden soil or sandboxes where infected cats may have defecated.
In the US, the most common way to get infected with the toxoplasmosis parasite is by eating raw meat or unwashed fruits and vegetables (Cornell, 2008).
Fortunately, most people have been exposed to or infected by Toxoplasma and already have immunity to the disease. People with weakened immune systems run the greatest risk of contracting toxoplasmosis.
Those in relatively good health will usually show no signs or simply have mild, flu-like symptoms. About 10-20% of people infected with toxoplasmosis will develop symptoms similar to flu or glandular fever. “Symptoms usually appear a week or two after infection, wax and wane and then subside gradually over a period of two weeks to several months.”
http://www.nytimes.com/1982/10/27/garden/personal-health-247906.html?pagewanted=2Some people have swollen lymph glands or muscle aches and pains that last for a month or more. In healthy people who show symptoms, a flu-like feeling is the most common (which may result in the mistaken diagnosis of infectious mononucleosis)
. These symptoms also include:
• fever
• swollen lymph nodes, especially in the neck
• headache
• muscle aches and pains
Occasionally, patients may complain of a sore throat. These symptoms can last for a month or more.
http://www.healthline.com/health/toxoplasmosis#Symptoms3These are the symptoms Coe showed. He didn’t have severe toxoplasmosis, which effects the brain, eyes and organs.
Researchers from the Massachusetts Institute of Technology in 2013 say they have discovered clues as to why a malaria-related parasite, called toxoplasma gondii, can cause blindness in some people but not in others.
Toxoplasmosis can be contracted a number of ways. Eating undercooked or contaminated meat can lead to infection, as well as consuming water contaminated with the parasite.
The investigators explain that strains of the toxoplasma gondii parasite that are found in North America and Europe are different from strains found in South America - which appear to cause more severe symptoms regardless of a person's immune system strength.
To find out why, the researchers infected mouse immune cells - known as macrophages - with 29 different strains of the toxoplasma gondii parasite.
From this, the investigators found that some South American and atypical North American strains of the parasite had a type 1 interferon response. This is an immune reaction that usually occurs during viral infection.
This response prompts a strong inflammation reaction in the host's immune cells, which the researchers believe could be the cause of the severe effects that these strains produce.
In the summer of 1984, the Royal Ballet, following a visit to Manchester, was dogged by bad luck. Many of the dancers were ill, affected by the blood disease toxoplasmosis, ‘possibly contracted in China’. Please note that they were diagnosed in the UK not in China as you claim.
The idea that Coe caught toxoplasmosis from a blood transfusion as you claim is extremely unlikely, and your so called evidence makes no sense.
For a start, known practice of blood doping at the time was almost entirely autologous. So if Coe had caught it this way then he would have caught it from his own blood! This is clearly nonsense.
The other option, that a well known face, Olympic champion and world record holder would go into some 3rd rate medical centre in a back street of a foreign country and allow someone else’s unscreened blood be pumped into him is even more ridiculous. There would be several people out there who would have known about this and the UK press would have found them by now.