Look at all the dirty people on this thread who wear either dirty shoes or sweaty socks or germy feet around the house.
I have a bathroom (well, kinda) next to the front door with a full sanitation pod. Feet to hair all made immaculate by a glorious steam cleaning. Clothes get burned, of course, with a fresh set of plain white 100% Andean wool -soft as a baby's bottom, but, you know, clean - clothes. Top it all off with a UV flash to incinerate any germs left over.
This process is also repeated every time I or a guest should happen to use the bathroom.
Regarding containment breaches, the whole house can convert itself into an incinerator, so I leave, press the button, then can go in again to my 'reset' abode. I also like to do a reset monthly even if there are no breaches just because some particles of dust do happen to be smaller than the sensors can recognize. I'm still working to improve those sensors...