I gave a couple of advanced HS athletes a few double threshold workouts during their offseason training. These are talented, driven athletes that wanted to be training at a high level. However, before I felt comfortable assigning these workouts, I made sure they had the following under their belt:
1. The ability to comfortably double multiple times per week. Easy day or workout day didn't matter, but I needed them to be comfortable running twice per day before having them do two workouts per day.
2. Have a solid base of functional muscular strength from resistance training (squats, deadlifts, etc) and durable mechanics (drills, steep 8 sec hill sprints, flying 30's).
3. The ability to complete a substantial single-session tempo/threshold session like 3 x 10 minutes at the proper intensity.
With those in place, we made sure to do the following:
1. We don't have a lactate meter, but talked extensively about how low the intensity should feel relative to other types of workouts.
2. Limited the total amount of time of reps to ~45 minutes split between the two sessions. If you look at the Ingebrigtsen training, they are usually doing ~60 minutes worth of reps split between two sessions, so doing 3/4th of that seemed about right.
3. Carefully monitored their recovery (how they felt, resting HR first thing in the morning, etc) to make sure they hadn't overdone it.
Both kids had excellent XC seasons, finishing in the top 5 of their competitive state meet. At their recent state meet for track, they both doubled and brought home two 1sts, a 2nd and a 5th while combining to drastically reset the school record books in the 800, 1600 and 3200.
TL:DR - A couple of talented, driven kids used double thresholds carefully in the offseason, and were very successful.