When I ran the marathon I was averaging 70 miles a week and ran a 38 low 10k.
When I ran the 37 minute 10k I was averaging 45 miles a week but I added interval sessions. That speed training made a difference for me.
In the marathon I blew up at mile 17 or so and at the end I threw up bile because I had run it on an empty stomach. I was really ill for a few hours after - cold and shaky.